human VPS25 shRNA silencing AAV

Cat. No: shAAV-227516

Availability: 4-5 weeks

Name: AAV-h-VPS25-shRNA

This is an AAV expressing shRNA for silencing of Human VPS25.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: VPS25
Gene Name: vacuolar protein sorting 25 homolog
Gene ID: 84313
Gene Synonyms: DERP9; EAP20; FAP20
ORF Size: 531 bp
RefSeq#: NM_032353
Gene Description: VPS25, VPS36 (MIM 610903), and SNF8 (MIM 610904) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. VPS25, VPS36, and SNF8 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 (PubMed 15755741); Kamura et al., 2001 (PubMed 11278625)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.500165
HGNC ID: HGNC:28122