human VEGFC shRNA silencing AAV

Cat. No: shAAV-227459

Availability: 6-8 weeks

Name: AAV-h-VEGFC-shRNA

This is an AAV expressing shRNA for silencing of Human VEGFC.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: VEGFC
Gene Name: vascular endothelial growth factor C
Gene ID: 7424
Gene Synonyms: Flt4-L; LMPH1D; VRP
ORF Size: 1260 bp
RefSeq#: NM_005429
Gene Description: VEGFC is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
UniGene ID: Hs.435215
HGNC ID: HGNC:12682