human VCP shRNA silencing AAV

Cat. No: shAAV-227427

Availability: 4-5 weeks

Name: AAV-h-VCP-shRNA

This is an AAV expressing shRNA for silencing of Human VCP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: VCP
Gene Name: valosin containing protein
Gene ID: 7415
Gene Synonyms: ALS14; CMT2Y; HEL-220; HEL-S-70; IBMPFD; IBMPFD1; p97; TERA
ORF Size: 1428 bp
RefSeq#: NM_007126
Gene Description: VCP is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
UniGene ID: Hs.529782
HGNC ID: HGNC:12666