human UPP1 shRNA silencing AAV

Cat. No: shAAV-227236

Availability: 4-5 weeks

Name: AAV-h-UPP1-shRNA

This is an AAV expressing shRNA for silencing of Human UPP1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: UPP1
Gene Name: uridine phosphorylase 1
Gene ID: 7378
Gene Synonyms: UDRPASE; UP; UPASE; UPP
ORF Size: 522 bp
RefSeq#: NM_003364
Gene Description: The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 (PubMed 7488099)).(supplied by OMIM, Aug 2009)
UniGene ID: Hs.488240
HGNC ID: HGNC:12576