human UNC119 shRNA silencing AAV

Cat. No: shAAV-227180

Availability: 4-5 weeks

Name: AAV-h-UNC119-shRNA

This is an AAV expressing shRNA for silencing of Human UNC119.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: UNC119
Gene Name: unc-119 lipid binding chaperone
Gene ID: 9094
Gene Synonyms: HRG4; IMD13; POC7; POC7A
ORF Size: 723 bp
RefSeq#: NM_005148
Gene Description: UNC119 is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene.
UniGene ID: Hs.410455
HGNC ID: HGNC:12565