human UGCG shRNA silencing AAV

Cat. No: shAAV-227133

Availability: 4-5 weeks

Name: AAV-h-UGCG-shRNA

This is an AAV expressing shRNA for silencing of Human UGCG.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: UGCG
Gene Name: UDP-glucose ceramide glucosyltransferase
Gene ID: 7357
Gene Synonyms: GCS; GLCT1
ORF Size: 1185 bp
RefSeq#: NM_003358
Gene Description: Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation.
UniGene ID: Hs.593014
HGNC ID: HGNC:12524