human UBE2M shRNA silencing AAV

Cat. No: shAAV-227024

Availability: 4-5 weeks

Name: AAV-h-UBE2M-shRNA

This is an AAV expressing shRNA for silencing of Human UBE2M.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: UBE2M
Gene Name: ubiquitin conjugating enzyme E2 M
Gene ID: 9040
Gene Synonyms: hUbc12; UBC-RS2; UBC12
ORF Size: 552 bp
RefSeq#: NM_003969
Gene Description: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.
UniGene ID: Hs.406068
HGNC ID: HGNC:12491