human U2AF1 shRNA silencing AAV

Cat. No: shAAV-226951

Availability: 4-5 weeks

Name: AAV-h-U2AF1-shRNA

This is an AAV expressing shRNA for silencing of Human U2AF1.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: U2AF1
Gene Name: U2 small nuclear RNA auxiliary factor 1
Gene ID: 7307
Gene Synonyms: FP793; RN; RNU2AF1; U2AF35; U2AFBP
ORF Size: 504 bp
RefSeq#: NM_006758
Gene Description: U2AF1 belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF1 encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.
UniGene ID: Hs.365116
HGNC ID: HGNC:12453