human TYW1 shRNA silencing AAV

Cat. No: shAAV-226945

Availability: 4-5 weeks

Name: AAV-h-TYW1-shRNA

This is an AAV expressing shRNA for silencing of Human TYW1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TYW1
Gene Name: tRNA-yW synthesizing protein 1 homolog
Gene ID: 55253
Gene Synonyms: RSAFD1; TYW1A; YPL207W
ORF Size: 1155 bp
RefSeq#: NM_018264
Gene Description: Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW1 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.520917
HGNC ID: HGNC:25598