human TSPO shRNA silencing AAV

Cat. No: shAAV-226654

Availability: 4-5 weeks

Name: AAV-h-TSPO-shRNA

This is an AAV expressing shRNA for silencing of Human TSPO.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TSPO
Gene Name: translocator protein (18kDa)
Gene ID: 706
Gene Synonyms: BPBS; BZRP; DBI; IBP; MBR; mDRC; PBR; PBS; pk18; PKBS; PTBR;
ORF Size: 510 bp
RefSeq#: NM_000714
Gene Description: Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.
UniGene ID: Hs.202
HGNC ID: HGNC:1158