human TSPAN4 shRNA silencing AAV

Cat. No: shAAV-226646

Availability: 4-5 weeks

Name: AAV-h-TSPAN4-shRNA

This is an AAV expressing shRNA for silencing of Human TSPAN4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TSPAN4
Gene Name: tetraspanin 4
Gene ID: 7106
Gene Synonyms: NAG-2; NAG2; TETRASPAN; TM4SF7; TSPAN-4
ORF Size: 717 bp
RefSeq#: NM_001025239
Gene Description: TSPAN4 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
UniGene ID: Hs.654836
HGNC ID: HGNC:11859