human TSC22D3 shRNA silencing AAV

Cat. No: shAAV-226582

Availability: 4-5 weeks

Name: AAV-h-TSC22D3-shRNA

This is an AAV expressing shRNA for silencing of Human TSC22D3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TSC22D3
Gene Name: TSC22 domain family member 3
Gene ID: 1831
Gene Synonyms: DIP; DSIPI; GILZ; TSC-22R
ORF Size: 405 bp
RefSeq#: NM_004089
Gene Description: TSC22D3 shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine. Transcript variants encoding different isoforms have been identified for this gene.
UniGene ID: Hs.716410
HGNC ID: HGNC:3051