human TRIM63 shRNA silencing AAV

Cat. No: shAAV-226473

Availability: 6-8 weeks

Name: AAV-h-TRIM63-shRNA

This is an AAV expressing shRNA for silencing of Human TRIM63.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TRIM63
Gene Name: tripartite motif containing 63
Gene ID: 84676
Gene Synonyms: IRF; MURF1; MURF2; RNF28; SMRZ
ORF Size: 1062 bp
RefSeq#: NM_032588
Gene Description: TRIM63 encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.
UniGene ID: Hs.279709
HGNC ID: HGNC:16007