human TRDMT1 shRNA silencing AAV

Cat. No: shAAV-226362

Availability: 4-5 weeks

Name: AAV-h-TRDMT1-shRNA

This is an AAV expressing shRNA for silencing of Human TRDMT1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TRDMT1
Gene Name: tRNA aspartic acid methyltransferase 1
Gene ID: 1787
Gene Synonyms: DMNT2; DNMT2; MHSAIIP; PUMET; RNMT1
ORF Size: 1176 bp
RefSeq#: NM_004412
Gene Description: TRDMT1 encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.
UniGene ID: Hs.351665
HGNC ID: HGNC:2977