human TRAIP shRNA silencing AAV

Cat. No: shAAV-226336

Availability: 4-5 weeks

Name: AAV-h-TRAIP-shRNA

This is an AAV expressing shRNA for silencing of Human TRAIP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TRAIP
Gene Name: TRAF interacting protein
Gene ID: 10293
Gene Synonyms: RNF206; SCKL9; TRIP
ORF Size: 1410 bp
RefSeq#: NM_005879
Gene Description: TRAIP encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
UniGene ID: Hs.517972
HGNC ID: HGNC:30764