human TRAF5 shRNA silencing AAV

Cat. No: shAAV-226333

Availability: 4-5 weeks

Name: AAV-h-TRAF5-shRNA

This is an AAV expressing shRNA for silencing of Human TRAF5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TRAF5
Gene Name: TNF receptor associated factor 5
Gene ID: 7188
Gene Synonyms: MGC:39780; RNF84
ORF Size: 1674 bp
RefSeq#: NM_004619
Gene Description: The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized.
UniGene ID: Hs.523930
HGNC ID: HGNC:12035