human TPBG shRNA silencing AAV

Cat. No: shAAV-226243

Availability: 4-5 weeks

Name: AAV-h-TPBG-shRNA

This is an AAV expressing shRNA for silencing of Human TPBG.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TPBG
Gene Name: trophoblast glycoprotein
Gene ID: 7162
Gene Synonyms: 5T4; 5T4AG; M6P1; WAIF1
ORF Size: 1263 bp
RefSeq#: NM_006670
Gene Description: TPBG encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.
UniGene ID: Hs.82128
HGNC ID: HGNC:12004