human TOLLIP shRNA silencing AAV

Cat. No: shAAV-226174

Availability: 4-5 weeks

Name: AAV-h-TOLLIP-shRNA

This is an AAV expressing shRNA for silencing of Human TOLLIP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TOLLIP
Gene Name: toll interacting protein
Gene ID: 54472
Gene Synonyms: IL-1RAcPIP
ORF Size: 825 bp
RefSeq#: NM_019009
Gene Description: TOLLIP encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase.
UniGene ID: Hs.368527
HGNC ID: HGNC:16476