human TMEM70 shRNA silencing AAV

Cat. No: shAAV-225952

Availability: 4-5 weeks

Name: AAV-h-TMEM70-shRNA

This is an AAV expressing shRNA for silencing of Human TMEM70.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TMEM70
Gene Name: transmembrane protein 70
Gene ID: 54968
Gene Synonyms: MC5DN2
ORF Size: 783 bp
RefSeq#: NM_017866
Gene Description: TMEM70 likely encodes a mitochondrial membrane protein. The encoded protein may play a role in biogenesis of mitochondrial ATP synthase. Mutations in this gene have been associated with neonatal mitochondrial encephalocardiomyopathy due to ATP synthase deficiency. Alternatively spliced transcript variants have been described.
UniGene ID: Hs.106650
HGNC ID: HGNC:26050