human TMEM195 shRNA silencing AAV

Cat. No: shAAV-225833

Availability: 6-8 weeks

Name: AAV-h-TMEM195-shRNA

This is an AAV expressing shRNA for silencing of Human AGMO.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AGMO
Gene Name: alkylglycerol monooxygenase
Gene ID: 392636
Gene Synonyms: TMEM195
ORF Size: 1338 bp
RefSeq#: NM_001004320
Gene Description: AGMO is a tetrahydrobiopterin- and iron-dependent enzyme that cleaves the ether bond of alkylglycerols. Sequence comparisons distinguish this protein as forming a third, distinct class of tetrahydrobiopterin-dependent enzymes. Variations in this gene have been associated with decreased glucose-stimulated insulin response, type 2 diabetes, and susceptibility to intracranial aneurysms.
UniGene ID: Hs.670634
HGNC ID: HGNC:33784