human TMED10 shRNA silencing AAV

Cat. No: shAAV-225672

Availability: 4-5 weeks

Name: AAV-h-TMED10-shRNA

This is an AAV expressing shRNA for silencing of Human TMED10.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TMED10
Gene Name: transmembrane p24 trafficking protein 10
Gene ID: 10972
Gene Synonyms: p23; P24(DELTA); p24d1; S31I125; S31III125; Tmp-21-I; TMP21
ORF Size: 660 bp
RefSeq#: NM_006827
Gene Description: TMED10 is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. TMED10 has a pseudogene on chromosome 8.
UniGene ID: Hs.74137
HGNC ID: HGNC:16998