human TINAG shRNA silencing AAV

Cat. No: shAAV-225535

Availability: 6-8 weeks

Name: AAV-h-TINAG-shRNA

This is an AAV expressing shRNA for silencing of Human TINAG.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TINAG
Gene Name: tubulointerstitial nephritis antigen
Gene ID: 27283
Gene Synonyms: TIN-AG
ORF Size: 1431 bp
RefSeq#: NM_014464
Gene Description: TINAG encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the epithelium of Bowman's capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane nephritis. Ontogeny studies suggest that the expression of this antigen is developmentally regulated in a precise spatial and temporal pattern throughout nephrogenesis.
UniGene ID: Hs.127011
HGNC ID: HGNC:14599