human TIMP4 shRNA silencing AAV

Cat. No: shAAV-225534

Availability: 6-8 weeks

Name: AAV-h-TIMP4-shRNA

This is an AAV expressing shRNA for silencing of Human TIMP4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TIMP4
Gene Name: TIMP metallopeptidase inhibitor 4
Gene ID: 7079
ORF Size: 675 bp
RefSeq#: NM_003256
Gene Description: TIMP4 belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
UniGene ID: Hs.591665
HGNC ID: HGNC:11823