human TICAM1 shRNA silencing AAV

Cat. No: shAAV-225491

Availability: 6-8 weeks

Name: AAV-h-TICAM1-shRNA

This is an AAV expressing shRNA for silencing of Human TICAM1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TICAM1
Gene Name: toll like receptor adaptor molecule 1
Gene ID: 148022
Gene Synonyms: IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF
ORF Size: 2139 bp
RefSeq#: NM_182919
Gene Description: TICAM1 encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.
UniGene ID: Hs.29344
HGNC ID: HGNC:18348