human TIAL1 shRNA silencing AAV

Cat. No: shAAV-225486

Availability: 4-5 weeks

Name: AAV-h-TIAL1-shRNA

This is an AAV expressing shRNA for silencing of Human TIAL1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TIAL1
Gene Name: TIA1 cytotoxic granule associated RNA binding protein like 1
Gene ID: 7073
Gene Synonyms: TCBP; TIAR
ORF Size: 759 bp
RefSeq#: NM_003252
Gene Description: TIAL1 is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
UniGene ID: Hs.501203
HGNC ID: HGNC:11804