human THNSL2 shRNA silencing AAV

Cat. No: shAAV-225447

Availability: 6-8 weeks

Name: AAV-h-THNSL2-shRNA

This is an AAV expressing shRNA for silencing of Human THNSL2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: THNSL2
Gene Name: threonine synthase like 2
Gene ID: 55258
Gene Synonyms: SOFAT; THS2; TSH2
ORF Size: 1218 bp
RefSeq#: NM_018271
Gene Description: THNSL2 encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants.
UniGene ID: Hs.516179
HGNC ID: HGNC:25602