human TFAP2B shRNA silencing AAV

Cat. No: shAAV-225345

Availability: 6-8 weeks

Name: AAV-h-TFAP2B-shRNA

This is an AAV expressing shRNA for silencing of Human TFAP2B.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TFAP2B
Gene Name: transcription factor AP-2 beta
Gene ID: 7021
Gene Synonyms: AP-2B; AP2-B; PDA2
ORF Size: 1383 bp
RefSeq#: NM_003221
Gene Description: TFAP2B encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
UniGene ID: Hs.33102
HGNC ID: HGNC:11743