human TEC shRNA silencing AAV

Cat. No: shAAV-225283

Availability: 4-5 weeks

Name: AAV-h-TEC-shRNA

This is an AAV expressing shRNA for silencing of Human TEC.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TEC
Gene Name: tec protein tyrosine kinase
Gene ID: 7006
Gene Synonyms: PSCTK4
ORF Size: 1896 bp
RefSeq#: NM_003215
Gene Description: TEC belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
UniGene ID: Hs.479670
HGNC ID: HGNC:11719