human TAZ shRNA silencing AAV

Cat. No: shAAV-225052

Availability: 4-5 weeks

Name: AAV-h-TAZ-shRNA

This is an AAV expressing shRNA for silencing of Human TAZ.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TAZ
Gene Name: tafazzin
Gene ID: 6901
Gene Synonyms: BTHS; CMD3A; EFE; EFE2; G4.5; LVNCX; Taz1
ORF Size: 789 bp
RefSeq#: NM_000116
Gene Description: TAZ encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.
UniGene ID: Hs.409911
HGNC ID: HGNC:11577