human TAX1BP1 shRNA silencing AAV

Cat. No: shAAV-225050

Availability: 4-5 weeks

Name: AAV-h-TAX1BP1-shRNA

This is an AAV expressing shRNA for silencing of Human TAX1BP1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TAX1BP1
Gene Name: Tax1 binding protein 1
Gene ID: 8887
Gene Synonyms: CALCOCO3; T6BP; TXBP151
ORF Size: 2370 bp
RefSeq#: NM_006024
Gene Description: TAX1BP1 encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.34576
HGNC ID: HGNC:11575