human TAT shRNA silencing AAV

Cat. No: shAAV-225042

Availability: 6-8 weeks

Name: AAV-h-TAT-shRNA

This is an AAV expressing shRNA for silencing of Human TAT.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TAT
Gene Name: tyrosine aminotransferase
Gene ID: 6898
ORF Size: 1365 bp
RefSeq#: NM_000353
Gene Description: This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked.
UniGene ID: Hs.161640
HGNC ID: HGNC:11573