human SYTL5 shRNA silencing AAV

Cat. No: shAAV-224871

Availability: 6-8 weeks

Name: AAV-h-SYTL5-shRNA

This is an AAV expressing shRNA for silencing of Human SYTL5.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SYTL5
Gene Name: synaptotagmin like 5
Gene ID: 94122
Gene Synonyms: slp5
ORF Size: 2259 bp
RefSeq#: NM_138780
Gene Description: SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.662334
HGNC ID: HGNC:15589