human SYTL2 shRNA silencing AAV

Cat. No: shAAV-224865

Availability: 4-5 weeks

Name: AAV-h-SYTL2-shRNA

This is an AAV expressing shRNA for silencing of Human SYTL2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SYTL2
Gene Name: synaptotagmin like 2
Gene ID: 54843
Gene Synonyms: CHR11SYT; EXO4; PPP1R151; SGA72M; SLP2; SLP2A
ORF Size: 2808 bp
RefSeq#: NM_032379
Gene Description: SYTL2 is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
UniGene ID: Hs.369520
HGNC ID: HGNC:15585