human SYT14 shRNA silencing AAV

Cat. No: shAAV-224845

Availability: 6-8 weeks

Name: AAV-h-SYT14-shRNA

This is an AAV expressing shRNA for silencing of Human SYT14.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SYT14
Gene Name: synaptotagmin 14
Gene ID: 255928
Gene Synonyms: SCAR11; sytXIV
ORF Size: 1809 bp
RefSeq#: NM_153262
Gene Description: SYT14 is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in this gene are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t(1;3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4.
UniGene ID: Hs.658866
HGNC ID: HGNC:23143