human STRA6 shRNA silencing AAV

Cat. No: shAAV-224631

Availability: 6-8 weeks

Name: AAV-h-STRA6-shRNA

This is an AAV expressing shRNA for silencing of Human STRA6.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: STRA6
Gene Name: stimulated by retinoic acid 6
Gene ID: 64220
Gene Synonyms: MCOPCB8; MCOPS9; PP14296
ORF Size: 2004 bp
RefSeq#: NM_022369
Gene Description: STRA6 is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene.
UniGene ID: Hs.24553
HGNC ID: HGNC:30650