human STOM shRNA silencing AAV

Cat. No: shAAV-224614

Availability: 6-8 weeks

Name: AAV-h-STOM-shRNA

This is an AAV expressing shRNA for silencing of Human STOM.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: STOM
Gene Name: stomatin
Gene ID: 2040
Gene Synonyms: BND7; EPB7; EPB72
ORF Size: 867 bp
RefSeq#: NM_004099
Gene Description: STOM encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.253903
HGNC ID: HGNC:3383