human STK11 shRNA silencing AAV

Cat. No: shAAV-224574

Availability: 4-5 weeks

Name: AAV-h-STK11-shRNA

This is an AAV expressing shRNA for silencing of Human STK11.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: STK11
Gene Name: serine/threonine kinase 11
Gene ID: 6794
Gene Synonyms: hLKB1; LKB1; PJS
ORF Size: 1302 bp
RefSeq#: NM_000455
Gene Description: This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
UniGene ID: Hs.515005
HGNC ID: HGNC:11389