human STAR shRNA silencing AAV

Cat. No: shAAV-224513

Availability: 6-8 weeks

Name: AAV-h-STAR-shRNA

This is an AAV expressing shRNA for silencing of Human STAR.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: STAR
Gene Name: steroidogenic acute regulatory protein
Gene ID: 6770
Gene Synonyms: STARD1
ORF Size: 858 bp
RefSeq#: NM_000349
Gene Description: STAR plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
UniGene ID: Hs.521535
HGNC ID: HGNC:11359