human SRI shRNA silencing AAV

Cat. No: shAAV-224331

Availability: 4-5 weeks

Name: AAV-h-SRI-shRNA

This is an AAV expressing shRNA for silencing of Human SRI.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SRI
Gene Name: sorcin
Gene ID: 6717
Gene Synonyms: CP-22; CP22; SCN; V19
ORF Size: 597 bp
RefSeq#: NM_003130
Gene Description: SRI encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.
UniGene ID: Hs.489040
HGNC ID: HGNC:11292