human SPG11 shRNA silencing AAV

Cat. No: shAAV-224160

Availability: 4-5 weeks

Name: AAV-h-SPG11-shRNA

This is an AAV expressing shRNA for silencing of Human SPG11.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SPG11
Gene Name: spastic paraplegia 11 (autosomal recessive)
Gene ID: 80208
Gene Synonyms: ALS5; CMT2X; KIAA1840
ORF Size: 6993 bp
RefSeq#: NM_025137
Gene Description: SPG11 is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.683876
HGNC ID: HGNC:11226