human SP100 shRNA silencing AAV

Cat. No: shAAV-224036

Availability: 4-5 weeks

Name: AAV-h-SP100-shRNA

This is an AAV expressing shRNA for silencing of Human SP100.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SP100
Gene Name: SP100 nuclear antigen
Gene ID: 6672
Gene Synonyms: lysp100b
ORF Size: 1443 bp
RefSeq#: NM_003113
Gene Description: SP100 encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
UniGene ID: Hs.369056
HGNC ID: HGNC:11206