human SNRPC shRNA silencing AAV

Cat. No: shAAV-223880

Availability: 4-5 weeks

Name: AAV-h-SNRPC-shRNA

This is an AAV expressing shRNA for silencing of Human SNRPC.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SNRPC
Gene Name: small nuclear ribonucleoprotein polypeptide C
Gene ID: 6631
Gene Synonyms: U1C; Yhc1
ORF Size: 480 bp
RefSeq#: NM_003093
Gene Description: SNRPC encodes one of the specific protein components of the U1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. The encoded protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. The genome contains several pseudogenes of this functional gene. Alternative splicing results in a non-coding transcript variant.
UniGene ID: Hs.1063
HGNC ID: HGNC:11157