human SNRPA shRNA silencing AAV

Cat. No: shAAV-223872

Availability: 4-5 weeks

Name: AAV-h-SNRPA-shRNA

This is an AAV expressing shRNA for silencing of Human SNRPA.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SNRPA
Gene Name: small nuclear ribonucleoprotein polypeptide A
Gene ID: 6626
Gene Synonyms: Mud1; U1-A; U1A
ORF Size: 849 bp
RefSeq#: NM_004596
Gene Description: SNRPA associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
UniGene ID: Hs.466775
HGNC ID: HGNC:11151