human SMAD3 shRNA silencing AAV

Cat. No: shAAV-223691

Availability: 4-5 weeks

Name: AAV-h-SMAD3-shRNA

This is an AAV expressing shRNA for silencing of Human SMAD3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SMAD3
Gene Name: SMAD family member 3
Gene ID: 4088
Gene Synonyms: HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3
ORF Size: 1278 bp
RefSeq#: NM_005902
Gene Description: SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
UniGene ID: Hs.714621
HGNC ID: HGNC:6769