human SLC6A5 shRNA silencing AAV

Cat. No: shAAV-223571

Availability: 6-8 weeks

Name: AAV-h-SLC6A5-shRNA

This is an AAV expressing shRNA for silencing of Human SLC6A5.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC6A5
Gene Name: solute carrier family 6 member 5
Gene ID: 9152
Gene Synonyms: GLYT-2; GLYT2; HKPX3; NET1
ORF Size: 2394 bp
RefSeq#: NM_004211
Gene Description: SLC6A5 encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea.
UniGene ID: Hs.136557
HGNC ID: HGNC:11051