human SLC30A10 shRNA silencing AAV

Cat. No: shAAV-223363

Availability: 6-8 weeks

Name: AAV-h-SLC30A10-shRNA

This is an AAV expressing shRNA for silencing of Human SLC30A10.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC30A10
Gene Name: solute carrier family 30 member 10
Gene ID: 55532
Gene Synonyms: HMDPC; HMNDYT1; ZnT-10; ZNT10; ZNT8; ZRC1
ORF Size: 1455 bp
RefSeq#: NM_018713
Gene Description: SLC30A10 is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene.
UniGene ID: Hs.679909
HGNC ID: HGNC:25355