human SLC29A3 shRNA silencing AAV

Cat. No: shAAV-223330

Availability: 4-5 weeks

Name: AAV-h-SLC29A3-shRNA

This is an AAV expressing shRNA for silencing of Human SLC29A3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC29A3
Gene Name: solute carrier family 29 member 3
Gene ID: 55315
Gene Synonyms: ENT3; HCLAP; HJCD; PHID
ORF Size: 1428 bp
RefSeq#: NM_018344
Gene Description: SLC29A3 encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.
UniGene ID: Hs.438419
HGNC ID: HGNC:23096