human SLC25A4 shRNA silencing AAV

Cat. No: shAAV-223278

Availability: 4-5 weeks

Name: AAV-h-SLC25A4-shRNA

This is an AAV expressing shRNA for silencing of Human SLC25A4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC25A4
Gene Name: solute carrier family 25 member 4
Gene ID: 291
Gene Synonyms: AAC1; ANT; ANT 1; ANT1; MTDPS12; MTDPS12A; PEO2; PEO3; PEOA2; T1
ORF Size: 897 bp
RefSeq#: NM_001151
Gene Description: SLC25A4 is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy.
UniGene ID: Hs.246506
HGNC ID: HGNC:10990