human SLC25A20 shRNA silencing AAV

Cat. No: shAAV-223237

Availability: 4-5 weeks

Name: AAV-h-SLC25A20-shRNA

This is an AAV expressing shRNA for silencing of Human SLC25A20.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC25A20
Gene Name: solute carrier family 25 member 20
Gene ID: 788
Gene Synonyms: CAC; CACT
ORF Size: 906 bp
RefSeq#: NM_000387
Gene Description: SLC25A20 product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
UniGene ID: Hs.13845
HGNC ID: HGNC:1421