human SLC18A2 shRNA silencing AAV

Cat. No: shAAV-223157

Availability: 6-8 weeks

Name: AAV-h-SLC18A2-shRNA

This is an AAV expressing shRNA for silencing of Human SLC18A2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC18A2
Gene Name: solute carrier family 18 member A2
Gene ID: 6571
Gene Synonyms: SVAT; SVMT; VAT2; VMAT2
ORF Size: 1545 bp
RefSeq#: NM_003054
Gene Description: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 (PubMed 7905859)). See also SLC18A1 (MIM 193002).(supplied by OMIM, Jan 2011)
UniGene ID: Hs.654476
HGNC ID: HGNC:10935